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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS3
All Species:
21.82
Human Site:
Y446
Identified Species:
43.64
UniProt:
Q68E01
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68E01
NP_075391.3
1043
118070
Y446
C
R
I
I
P
N
F
Y
P
P
L
E
G
H
V
Chimpanzee
Pan troglodytes
XP_001143923
1108
125002
Y445
C
R
I
I
P
N
F
Y
P
P
L
E
G
H
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852591
1046
117423
Y443
C
R
I
I
P
N
F
Y
P
P
L
E
G
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPD0
1041
117919
Y444
C
R
I
I
P
N
F
Y
P
P
L
E
G
H
V
Rat
Rattus norvegicus
XP_342289
1041
117877
Y444
C
R
I
I
P
N
F
Y
P
P
L
E
G
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235108
302
34498
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LXC9
1017
116384
F422
C
R
I
I
P
H
F
F
P
P
L
E
G
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLS8
1068
123932
F422
C
R
I
T
K
N
F
F
V
K
H
E
D
K
I
Honey Bee
Apis mellifera
XP_394651
1035
118020
Y418
C
R
I
I
P
N
F
Y
P
P
L
T
E
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786914
388
44969
Poplar Tree
Populus trichocarpa
XP_002298478
995
112510
E410
L
F
I
A
E
N
Y
E
E
D
R
N
Y
V
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193195
508
59017
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
N.A.
93.9
N.A.
98.5
98.3
N.A.
N.A.
25.5
N.A.
83.3
N.A.
39
46
N.A.
24.2
Protein Similarity:
100
94
N.A.
95
N.A.
99.3
99.2
N.A.
N.A.
27.5
N.A.
91
N.A.
60
66.9
N.A.
29.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
0
N.A.
80
N.A.
40
80
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
0
N.A.
93.3
N.A.
53.3
80
N.A.
0
Percent
Protein Identity:
24.6
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
43.6
N.A.
N.A.
33.4
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% D
% Glu:
0
0
0
0
9
0
0
9
9
0
0
59
9
0
0
% E
% Phe:
0
9
0
0
0
0
67
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
9
0
0
42
0
% H
% Ile:
0
0
75
59
0
0
0
0
0
0
0
0
0
0
17
% I
% Lys:
0
0
0
0
9
0
0
0
0
9
0
0
0
17
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
67
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
59
0
0
0
59
59
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
67
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
50
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _